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Testosterone (TRT)

5 min read

Is Testosterone Replacement Therapy (TRT) for Men Safe?

testosterone replacement therapy

Testosterone. It’s the hormone synonymous with masculinity, associated with libido, strength and vitality. So, there is no wonder that as we age, testosterone levels naturally decline. 

Nowadays, some men recapture their youth through a magic treatment: Testosterone Replacement Therapy or TRT. In recent days, TRT has gained immense popularity to treat a variety of conditions, particularly those associated with aging in men. From boosting energy levels to enhancing muscle mass and libido, the promises of TRT seem enticing. 

But hold onto your hats, gentlemen. Before diving into these treatments, it is essential to understand the potential risks and benefits. 

The Low Down on Low T

Marketers urge men to talk to their doctors if they exhibit certain “Possible Signs” of low testosterone. Many men inquire about it after seeing ads that ask, “Do you feel tired?”.

Low Testosterone in men, medically known as Hypogonadism, can cause a constellation of various symptoms. 

Signs of LowT:

  • Low sex drive
  • Fatigue
  • Mood Changes
  • Erectile Dysfunction
  • Decline in Muscle mass
  • Depression and difficulty in concentration

However, it is important to know that not everyone experiencing these symptoms has low testosterone. General fatigue and malaise have many causes, and most men who get tested find their testosterone levels are normal.

There are other medical conditions that can mimic these symptoms and a simple blood test can determine your testosterone levels. Testosterone Replacement Therapy often needs to be continued indefinitely, as stopping it can lead to noticeable changes due to the body’s reduced testosterone production.

TRT for Men: A Boon or a Bane?

When diagnosed with lowT or Hypogonadism and experiencing bothersome symptoms, Testosterone Replacement Therapy for Men can be a game-changer. It aims to restore your hormone levels to a more youthful state. It can be administered through injections, patches, gels or implants. While it is marketed as a solution to combat the effects of aging, the safety and efficacy of TRT remain subjects of debates. Check out our previous blog on TRT for Men: Everything You Need to Know to learn more.

The Potential Benefits of Testosterone Replacement Therapy:

1. Improved Mood and Mental Health:

Many men report improved mood and reduced symptoms of depression after starting testosterone therapy. This is likely due to the hormone’s influence on neurotransmitters in the brain.

2. Enhanced Libido and Sexual Function:

One of the most well-documented benefits of testosterone replacement therapy (TRT) is its impact on sexual health. Increased libido and improved erectile function are commonly reported outcomes.

3. Increased Muscle Mass and Strength:

Testosterone is crucial for muscle development. So, TRT for men can lead to increased muscle mass and strength, which is particularly beneficial for those experiencing age-related muscle loss.

4. Better Bone Density:

Higher testosterone levels can improve bone density. It is also well-known for reducing the risk of osteoporosis and fractures in older men.

5. Increased Energy Levels:

Many men undergoing testosterone therapy report higher energy levels and reduced fatigue, contributing to a better quality of life.

However, TRT is not a magic bullet. It comes with a potential side effect profile that should not be ignored. 

Check out our blog on understanding Free Testosterone and Its Impact on Your Body to learn more.

Potential Risks of Testosterone Replacement Therapy (TRT):

Some men experience immediate side effects of Testosterone supplementation, such as acne, disturbed breathing while sleeping, breast swelling or tenderness and swelling in the ankles. Doctors also monitor for high red blood cell counts, which could increase the risk of clotting.

Older observational studies suggested long-term testosterone use could develop various risks. 

1. Cardiovascular Issues:

One of the most significant concerns is the potential link between testosterone replacement therapy (TRT) and cardiovascular problems. Some studies suggest that testosterone therapy might increase the risk of heart attacks, strokes, and other cardiovascular events, particularly in older men or those with pre existing heart conditions.

2. Prostate Health:

Testosterone can stimulate the growth of prostate cells, which may exacerbate benign prostatic hyperplasia (BPH) or increase the risk of prostate cancer. Men considering testosterone therapy should undergo thorough screening for prostate health.

3. Sleep Apnea:

TRT or testosterone therapy can worsen sleep apnea, a serious sleep disorder where breathing repeatedly stops and starts. This can lead to poor sleep quality and other health issues.

4. Blood Clots:

There is evidence suggesting that testosterone therapy might increase the risk of blood clots. This can lead to deep vein thrombosis (DVT) or pulmonary embolism, both of which are potentially life-threatening conditions.

5. Hormonal Imbalances:

TRT for men can disrupt the body’s natural hormone production, leading to conditions such as gynecomastia (enlarged breast tissue in men) and testicular shrinkage. Balancing hormone levels after stopping therapy can also be challenging.

What Are the Cautious Approaches to TRT for Men?

Here’s how to approach testosterone therapy cautiously:

  • Evaluate Your Health First:

Before considering TRT, assess other potential causes of fatigue, low sex drive, and related symptoms. Are you maintaining a balanced, nutritious diet? Do you exercise regularly? Are you getting enough quality sleep? Address these lifestyle factors before opting for hormone replacement therapy.

  • Consider Relationship and Psychological Factors:

If your sex life isn’t what it used to be, consider whether relationship or psychological issues might be contributing factors. Erectile dysfunction, often linked to “low T,” can also be a sign of cardiovascular disease.

  • Get an Accurate Assessment:

Testosterone levels should be measured between 7 am and 10 am when they peak. Confirm a low reading with a second test on a different day. Accurate diagnosis may require multiple tests and careful interpretation to determine bioavailable testosterone. Consider getting a second opinion from an endocrinologist.

  • Regular Monitoring After Starting Therapy:

After beginning therapy, regularly follow up with your physician for testosterone checks and other lab tests to ensure the therapy isn’t causing issues with your prostate or blood chemistry.

  • Understand the Risks of Testosterone Replacement Therapy:

Exercise caution with testosterone therapy if you have a high risk of prostate cancer, severe urinary symptoms from prostate enlargement, diagnosed heart disease, a history of heart attack, or multiple heart problem risk factors. Discuss the potential side effects of various testosterone formulations, such as injections, gels, and patches, with your doctor. Know what signs indicate problems.

  • Have Realistic Expectations:

Testosterone therapy is not a cure-all. It won’t restore your physical fitness or sexual function to youthful levels, extend your lifespan, prevent heart disease or prostate cancer, or significantly improve memory or mental sharpness. If erectile function is an issue, testosterone therapy might increase your sex drive without resolving the physical difficulties, necessitating additional medication or therapy.

The Final Word

Testosterone therapy or TRT for men can be a valuable tool to improve the quality of life for those with diagnosed hypogonadism. However, it’s not without risks.

Consult a qualified doctor, weigh the pros and cons carefully, and explore alternative lifestyle modifications before taking the plunge. With the right approach, you can manage your health and maintain a sense of well-being as you age.

Here at Precision Telemed, we provide personalized Testosterone Replacement Therapy (TRT) treatment plans according to your needs and medical conditions.

So, don’t hesitate further! Schedule your appointment today with our licensed physicians and revive yourself.

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