Dr. Palumbo, DO
Medical Director
Prescription-strength copper peptide face cream, compounded at 2.5% and reviewed by a board-certified physician before it ships.
GHK-Cu signals the skin processes behind collagen and elastin. Most over-the-counter serums stay under 1%. At 2.5%, this cream sits near the top of the compounded range, which is why it requires a prescription.
One transparent price: $179.99 for a 60-day supply, about $90 per month. Your physician consultation, prescription, and shipping are all included.

Cancel anytime. No long-term contract.
Copper Peptide Cream 2.5% is compounded for Precision Telemed by state-licensed 503A compounding pharmacies. Compounded preparations are customized to your prescription and are not reviewed by the FDA for safety or effectiveness. A prescription is issued only when a licensed physician determines it is appropriate for you.
The fastest way to buy copper peptides at prescription strength is a telehealth visit: assessment, physician review, delivery.
Answer a brief, secure questionnaire in under five minutes: your goals, skin history, and the products already in your routine.
Same-day consults are available. A prescription is issued only when your physician determines the cream is appropriate for you.
Your cream ships from a licensed 503A compounding pharmacy in discreet packaging within 48 hours.
Every copper peptide prescription is reviewed by a licensed clinician before it ships. Meet the team responsible for your care.
GHK-Cu, listed on ingredient labels as copper tripeptide-1, is a small copper-binding peptide found naturally in human plasma. Levels decline with age. Applied topically, it signals the skin processes behind collagen and elastin.
GHK-Cu binds copper and carries it into skin, where it acts as a signaling molecule for fibroblasts, the cells responsible for producing collagen and elastin. More signal supports the structure that keeps skin looking firm.
Pickart & Margolina, Int J Mol Sci, 2018Compounded GHK-Cu preparations typically range from 0.2% to 3%. At 2.5%, this GHK-Cu face cream sits near the top of that range, several times the concentration of typical retail serums. That strength is why it is dispensed by prescription, after a physician reviews your skin.
Both deliver GHK-Cu. The difference is concentration and how the format fits your routine.
Searching for the best copper peptide serum usually means trading strength for texture. If you want prescription-strength GHK-Cu in one moisturizing step, the 2.5% cream is the format we prescribe.
Copper peptides fit most routines with two simple rules: keep strong acids and pure vitamin C at a different time of day, and let retinol share the week rather than compete.
They work through different mechanisms and can share a routine. The simplest split is copper peptide cream in the morning, retinol at night, or alternating evenings if your skin runs sensitive. Retinoids remain the more extensively studied option for fine lines; copper peptides are the gentler, repair-focused partner, and a common choice on nights your skin needs a break.
Avoid layering copper peptides directly with pure vitamin C (L-ascorbic acid). The copper ion can interact with ascorbic acid and blunt what each does best. Use vitamin C with sunscreen in the morning and your copper peptide cream in the evening, or as your physician directs.
Topical GHK-Cu is generally well tolerated in published cosmetic research. Your physician reviews your skin history and current routine before prescribing.
Your physician makes the final call during your consultation, based on your health history and the products already in your routine.
Copper peptides reward consistency. Here is the realistic arc our physicians describe, based on published cosmetic research.
Skin typically feels softer and better hydrated first. This is the earliest change most people notice in copper peptides before and after photos.
With daily use, skin tends to look firmer and fine lines appear softened. Photograph yourself in consistent lighting to track it honestly.
Visible change generally plateaus here. Staying consistent maintains the result; stopping lets skin drift back over time.
Individual results vary. Copper peptide changes are appearance-based and depend on age, skin condition, sun protection, and consistency of use.
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GHK-Cu is one of the most studied cosmetic peptides, and published research associates it with firmer, smoother looking skin over 8 to 12 weeks of consistent use. Results are appearance based and vary from person to person, which is why every Precision Telemed prescription starts with a physician review.
Copper peptide cream delivers GHK-Cu, a copper binding peptide that signals the skin processes behind collagen and elastin. With daily use, skin typically looks firmer and more hydrated, texture feels smoother, and fine lines appear softened.
Most people notice texture and hydration changes in 2 to 4 weeks. Firmness and the look of fine lines typically improve over 8 to 12 weeks, with visible change plateauing around weeks 12 to 16. Individual results vary.
Yes. The simplest approach is copper peptide cream in the morning and retinol at night, or alternating evenings if your skin is sensitive. They work through different mechanisms and complement each other well.
Use them at different times of day rather than layered together. Pure vitamin C (L-ascorbic acid) can interact with the copper ion, so most routines put vitamin C in the morning and copper peptides in the evening.
Avoid applying copper peptides at the same time as pure vitamin C or strong exfoliating acids such as glycolic or salicylic acid. All of these can stay in your weekly routine, just at a different time of day than your copper peptide cream.
No, and we do not claim they are. Retinoids have a broader evidence base for fine lines and photoaging. Copper peptides are a gentler, repair focused complement, and a practical alternative for skin that cannot tolerate nightly retinoids.
Topical copper peptides are generally well tolerated. Occasional reports include mild redness, warmth, or tingling where applied, and dryness when combined with strong actives. Discontinue and contact your physician if irritation persists.
The blue color comes from the copper ion bound to the peptide itself, not from a dye. At concentrations up to 3%, skin staining is generally not noted.
Yes. Compounded copper peptide preparations typically range from 0.2% to 3%, which places 2.5% near the top of that range. Typical over-the-counter serums are under 1%, so 2.5% is meaningfully stronger and is prescribed with physician oversight.
It depends on your routine. Serums are lightweight layers, usually under 1% GHK-Cu, worn under a separate moisturizer. A 2.5% cream combines prescription strength with an emollient base in one step, which suits mature, dry, or sensitive skin.
Yes. At 2.5%, GHK-Cu cream is compounded by a licensed 503A pharmacy and requires a prescription. Precision Telemed physicians review your skin assessment online and prescribe only when it is appropriate for you.
Copper Peptide Cream 2.5% is $179.99 for a 60-day supply, which works out to about $90 per month. The price includes your physician consultation, prescription, and shipping, with no hidden fees. Cancel anytime.
GHK-Cu has been studied in scalp and hair research, which is why copper peptides appear in some hair products. Our 2.5% cream is prescribed for facial skin. If hair support is your goal, mention it during your consultation.
Medically reviewed by Joseph Palumbo, DO, Medical Director, Precision Telemed.
Copper peptide cream works on how skin looks from the outside. NAD+ supports cellular energy from within. Many patients run both under one physician’s care plan.
Prescription-strength copper peptides, reviewed by a physician before they ever touch your skin.
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